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Details of Grant 

EPSRC Reference: GR/N00456/01
Title: MOMENTUM SHIFT IMAGING IN POSITRON EMISSION TOMOGRAPHY
Principal Investigator: Spyrou, Professor NM
Other Investigators:
Britton, Professor K Lalmas, Dr M
Researcher Co-Investigators:
Project Partners:
Department: Physics
Organisation: Queen Mary University of London
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 2000 Ends: 31 January 2003 Value (£): 93,817
EPSRC Research Topic Classifications:
Image & Vision Computing
EPSRC Industrial Sector Classifications:
Healthcare No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
This proposal is concerned with the need to utilise the total information content of PET scans, a good deal of which is not used at present. The intention is to determine whether this extra data, if gathered using a high resolution detector, will result in the provision of clinically-useful information. To this end, the Doppler-Broadening of the annihilation radiation will be correlated with the controlled variation of oxygen content of quasi-biological materials. Preliminary data have already shown that there is such a correlation.Using the high resolution detector in a replicated PET scanner, a series of projections will be taken and a database of Doppler-Broadening parameters compiled for each projection. A Neural Network will be set up and trained on a human skull object that contains three positron sources of well-characterised parameters. When developed, the training scheme will be used to reconstruct the spatial position of the sources. The information content of the image can then be made in terms either of total activity or of the spatial extent of the degree of oxygenation.EngProg\
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