| EPSRC Reference: |
GR/R08834/01 |
| Title: |
From Micrograms To Multikilos |
| Principal Investigator: |
Gavriilidis, Professor A |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Biochemical Engineering |
| Organisation: |
UCL |
| Scheme: |
FORESIGHT LINK |
| Starts: |
30 April 2001 |
Ends: |
29 January 2005 |
Value (£): |
415,892
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
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| Related Grants: |
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Summary on Grant Application Form |
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Combinatorial chemistry has resulted in the more rapid discovery of lead-compounds in the pharmaceutical and agrochemical areas. As a consequence, bottle-necks occur when the lead-compounds need to be produced on a large scale, for which the techniques of combichem are inappropriate. The process of route-definition and scale-up extends the time-to-market. It is widely agreed that in the vast majority of cases the speedy implementation of a suitable manufacturing process will only be achieved by a focused team comprising synthetic organic chemists, physical organic chemists, analytical chemists and chemical engineers. The key is to begin with the commonalities: the link between chemists and chemical engineers is the chemical reaction itself. While it may not be the speciality of either, chemical kinetics and the physical properties of reacting systems are familiar to both groups. This proposal therefore begins with kinetics and brings the fruits of fundamental kinetic studies upstream into organic synthetic strategy, as well as downstream into reactor design. The chemical reaction is the link which may be used to help all parties in the process research and development spectrum to begin to speak a common language.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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