| EPSRC Reference: |
GR/S95589/01 |
| Title: |
Multiscale simulation of reactivity & biocompatibility ot titanium prostheses |
| Principal Investigator: |
Curtis, Dr R |
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| Department: |
Restorative Dentistry |
| Organisation: |
Kings College London |
| Scheme: |
Postdoctoral Mobility PreFEC |
| Starts: |
01 October 2004 |
Ends: |
30 September 2005 |
Value (£): |
75,285
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Summary on Grant Application Form |
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This Postdoctoral Mobility between Disciplines study will exchange knowledge between Materials Engineering, Implant Prosthodontics and Cellular Biology. A multiscale, multiphysics model originally developed for automotive and aerospace applications will be applied to the modelling of dental and maxillofacial prosthesis fabrication. As new manufacturing processes are developed and explored for the fabrication of implantable prostheses, difficulties may arise due to the very sensitive nature of the implant environment. By simulating the manufacturing process, such difficulties as nonuniformities in the internal stresses, contamination with impurities, and microstructural defects may be anticipated. In order to bring the process through to the final stage, a model of the complex environment in which the prosthesis is used will be developed. This will aim to assess problems originating in the manufacturing process that may affect the biocompatibility of the final device. In order to encourage postdoctoral mobility, a Materials Science research associate will undertake to obtain experimental results in implant biocompatibility in order to develop computational models for titanium implant fabrication and behaviour. This will involve characterization of the implant materials and the use of computational models developed by the RA, and cell culture techniques for assessing biocompatibility in vitro. The results of these studies will be used to develop relationships to form the basis of the modelling.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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