| EPSRC Reference: |
GR/N64472/01 |
| Title: |
DEVELOPMENT OF A FIBRE LASER STIMULATION SYSTEM & ITS APPLICATION TO FUNCTIONAL IMAGING OF PAIN PROCESSING |
| Principal Investigator: |
King, Professor T |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Physics & Astronomy |
| Organisation: |
Victoria University of Manchester, The |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 2000 |
Ends: |
31 March 2003 |
Value (£): |
186,996
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| EPSRC Research Topic Classifications: |
| Lasers & Optics |
Light-Matter Interactions |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
Pharmaceuticals and Biotechnology |
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Summary on Grant Application Form |
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Collaboration between the applicants has shown that laser induced pain stimulus in combination with psychophysical measurements and functional imaging is a valuable approach for the study of human pain processing.A novel pain stimulator is to be designed and developed using a newly developed Tm-silica fibre laser with tuning, computer modulation and control of output parameters. The system will have stable alignment, will not require bulky power supplies or water cooling and will be ideally suited for clinical application. The output will be fibre delivered to allow stimulation of various body sites, the flexibility to be used with pain patients, and cost-effective and convenient stimulation for functional imaging, particular in the case of the fMRI environment.The output parameters of the laser will be determined to produce the full range of pain experience, and matched to the requirements of the functional imaging techniques.The laser will be used in novel pain studies in conjunction with fMRI and EEG to investigate somatotopic mapping of nociceptive processing. The studies will allow optimisation of the laser system for EEG (time-locking, pulsing and triggering), and fMRI (delivery within the scanner and sensitivity), whilst making substantial contributions to our current knowledge of human pain processing.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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